A Comprehensive Guide to Neurotoxins

When most people think about wrinkle-relaxing injections, one word usually pops up: Botox. It's no surprise—Botox is the most recognized name in the aesthetic space. But here's something many don’t realize: "Botox" is just one of several FDA-approved neurotoxins available today. In fact, there are six neurotoxins approved for use in the U.S. Each one works similarly, yet offers unique benefits.

Whether you're new to injectables or have been curious for a while, this guide will walk you through everything you need to know. We’ll explain what neurotoxins are, how they work, clear up common misconceptions (like confusing Botox with filler), and help you understand your options.

What Are Neurotoxins?
Neurotoxins are purified proteins derived from botulinum toxin type A. They work by temporarily relaxing the muscles responsible for dynamic wrinkles—the lines that form from repeated expressions like frowning, smiling, or raising your brows. By relaxing those muscles, neurotoxins help smooth the overlying skin for a more refreshed and natural appearance.

FDA Approval: What It Actually Means
An FDA approval means a neurotoxin has gone through rigorous clinical trials and has been proven safe and effective for specific uses. For example, Botox was originally approved to treat glabellar lines (aka the "11s" between your brows). Since then, it has gained additional approvals for various medical and cosmetic applications.

Off-Label Use: Common and Safe in Aesthetics
In the aesthetic world, off-label use simply means using a product in a way that isn’t specified on its FDA label. It’s legal, widely practiced, and often how we achieve some of the best results. For example, neurotoxins are commonly used off-label to treat crow's feet, forehead lines, jaw tension, lip flips, and even neck bands.

When administered by trained professionals, off-label use is both safe and effective.

Typical Treatment Areas and Unit Ranges
Every face is unique, and your injector will customize your treatment plan based on your facial anatomy and muscle strength. But here are some typical unit guidelines:

• Glabella ("11s"): 20 units
• Crow’s Feet: 12 units per side
• Forehead Lines: 10–20 units

Different brands have slightly different potencies, so the number of units may vary. Always trust your provider to recommend the most effective dose for your face.

Meet the Six FDA-Approved Neurotoxins
Curious about which neurotoxin might be right for you? At Ananya Aesthetics, we offer all six FDA-approved options to tailor your treatment to your lifestyle, anatomy, and goals:

1. Botox Cosmetic (onabotulinumtoxinA)
This is the name you know—and for good reason. As the gold standard in the industry, Botox is celebrated for its consistency, safety, and versatility. It typically takes 4–7 days to start to see results, with effects lasting about 3–4 months. It’s a great all-around option that we confidently recommend for a wide range of patients.
2. Dysport (abobotulinumtoxinA)
Dysport kicks in fast—often within 2 to 3 days—and tends to diffuse more widely. That makes it ideal for larger treatment areas like the forehead. If you're looking for a quick refresh before an event or want fast-acting results, this might be the one for you.
3. Xeomin (incobotulinumtoxinA)
Known as the "naked" neurotoxin, Xeomin is free of complexing proteins, which may reduce the risk of developing resistance over time. It’s a smart choice for patients with sensitivities or who prefer minimalist formulations.
4. Jeuveau (prabotulinumtoxinA-xvfs)
This one is often dubbed "Newtox" because it was developed exclusively for aesthetic use. It’s a go-to for first-time patients, with a quick onset of 2–3 days and results lasting up to 3–4 months. Jeuveau is sleek, effective, and designed for beauty.
5. Daxxify (daxxibotulinumtoxinA-lanm)
If you want serious longevity, Daxxify delivers. With a peptide-powered formula, this neurotoxin can last up to 6 months—twice as long as traditional options. For those who prefer fewer appointments per year, it’s an excellent investment in long-term results.
6. Letybo (letibotulinumtoxinA)
The newest player in the field, Letybo emphasizes high purity and targeted precision. It kicks in quickly (2–3 days) and offers results on par with more established options. It’s gaining trust fast—and our team is excited to offer it.
What Makes Them Alike—and DifferentAll six neurotoxins are made from the same base: botulinum toxin type A. They all relax muscles and soften dynamic wrinkles. But each has subtle differences in onset, spread, formulation, and longevity. That’s why it’s so important to work with an injector who can choose the right one based on your anatomy, goals, and lifestyle.

Pre-Treatment Tips

• Avoid alcohol for 24 hours before treatment.
• Skip blood-thinning meds/supplements (like aspirin, ibuprofen, vitamin E, or fish oil) if safe to do so.
• No Retin-A 2 days before and after.
• Reschedule if you have a cold sore, blemish, or rash.
• Come well-fed and hydrated to avoid feeling lightheaded.

Post-Treatment Instructions

• Don’t rub or massage the area for at least 6 hours.
• Stay upright for 6 hours post-treatment.
• Skip facials, intense exercise, or saunas for 24–48 hours.
• Make the same facial expressions every 10 minutes for 2 hours (helps with spread of product).
• Results take up to 2 weeks. Need a touch-up? We only charge for what we use.

Choosing the Right Neurotoxin for You
This isn’t one-size-fits-all. Your skin goals, muscle movement, budget, and how long you want results to last all factor in. For example:

• Want fast results? Try Jeuveau or Dysport.
• Concerned about additives? Xeomin could be your pick.
• Hate coming in too often? Daxxify might be worth the investment.

Let us help you decide. Your consultation at Ananya Aesthetics is all about you—your face, your comfort, your goals.
Bonus: Neurotoxins Aren’t Just for Wrinkles

• Hyperhidrosis (excessive sweating): Neurotoxins can dramatically reduce underarm sweat.
• Chronic Migraines: Botox is FDA-approved to help lessen frequency and severity.

The world of neurotoxins is bigger than Botox, and that's a good thing. With more choices, we can better personalize your results. Whether you're just starting to explore your options or you're a seasoned pro, we’re here to answer all your questions and make you feel confident about your care.

Still curious? Book a consultation. We’ll talk through everything and help you find your best fit.